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BioSyntech manufactures a vast selection of thoroughly characterized and ultra pure chitosans, with various properties, under the name Ultrasan™.
BioSyntech has developed unique manufacturing processes to control the polymer's characteristics, purification techniques to eliminate contaminants, as well as reliable and validated analytical methods to certify the quality of the product.
Contaminants such as proteins, bacterial endotoxins, toxic metals, inorganics and other impurities are all under detectable levels.
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Ultrasan™ products are released with an exhaustive certificate of analysis documenting their purity and specifications.
For more information on our line of available Ultrasan™ products, visit our site:
Chitosan comes from the partial deacetylation of chitin, a natural biopolymer originating from crustacean shells.
Chitosan is a linear polysaccharide with interspersed D-glucosamine and acetyl-D-glucosamine units. The preponderance and distribution acetyl-D-glucosamine residues lead to interesting physicochemical properties and biological responses.
Chitosan has been shown in the scientific literature to:
- have antimicrobial and antifungal activities (Choi BK et al., 2001),
- be useful in promoting tissue growth in tissue repair (Mattioli-Belmonte M et al., 1997),
- accelerate wound-healing and bone regeneration (Mattioli-Belmonte M et al., 1997),
- be beneficial for drug delivery systems (Janes KA et al., 2001, Ruel-Gariepy E et al., 2000)
- Be hemostatic (Rao SB et al., 1997).
Links to references:
- Choi BK, et al. In vitro antimicrobial activity of a chitooligosaccharide mixture against Actinobacillus actinomycetemcomitans and Streptococcus mutans. Int J Antimicrob Agents 2001;18:553-557
- Mattioli-Belmonte M et al., Chitin and chitosan in wound healing and other biomedical applications, Carbohydrates in Europe, 1997; 19:30-36.
- Ruel-Gariepy E, et al. Characterization of thermosensitive chitosan gels for the sustained delivery of drugs. Int J Pharm 2000;203:89-98.
- Janes KA, et al. Chitosan nanoparticles as delivery systems for doxorubicin. J Controlled Release 2001;73:255-267.
- Rao SB et al., Use of chitosan as a biomaterial: studies on its safety and hemostatic potential, 1997; 34:21-28.