Biosyntech - Publications and Presentations

Publications and Presentations

BST-Gel®

Chenite A, Gori S, Shive M, DesRosiers E, Buschmann MD. Monolithic gelation of chitosan solutions via enzymatic hydrolysis of urea, Carbohydrate Polymers
Roughley P, Hoemann CD, DesRosiers E, Mwale F, Antoniou J, Alini M. The Potential of Chitosan-based Gels containing Intervertebral Disk Cells for Nucleus Pulposus Supplementation 2006 Biomaterials,27(3):388-396
Hoemann CD, Sun J, Légaré A, McKee MD, Buschmann MD. Tissue Engineering of Cartilage using an Injectable and Adhesive Chitosan-Based Cell-Delivery Vehicle, Osteoarthritis & Cartilage. 2005;13(4): 318-329
Rossomacha E, Hoemann C, Shive M, Simple Methods for Staining Chitosan in Biotechnological Applications, J Histotech, 2004;27:1, 31-36
Ruel-Gariépy E, Shive M, et al. A thermosensitive chitosan-based hydrogel for the local delivery of paclitaxel Euro J of Pharm and Biopharm, 2004;57: 53-63.

More references for BST-Gel®

Other references for BST-Gel®

Ruel-Gariépy E, Berrada M, Shive M, Leroux JC. Thermosensitive Chitosan–based Hydrogel for Intra-tumoral Delivery of Paclitaxel 30th Annual Meeting & Exposition of the Controlled Release Society, Glasgow, Scotland, July 19-23, 2003.
Ruel-Gariépy E, et al. Thermosensitive chitosan-based hydrogel containing liposomes for the delivery of hydrophilic molecules. Journal of Controlled Release, 2002;82 : 373-383. (359 KB)
Jarry C et al. Irradiating or Autoclaving Chitosan/Polyol Solutions: Effect on Themogelling Chitosan-ß-glycerophosphate Systems. Chem. Pharm. Bull. 2002;50 (10):1335-1340.
Jarry, C et al. Effects of polyols on sterilised chitosan solutions. In: Chitosan in pharmacy and chemistry, Muzzarelli R.A.A., Muzzarelli C. (eds), Grottammmare (Italy), ATEC, 2002, p.335-340.
Chenite A, Buschmann MD, Wang D, Chaput C, Kandani N. Rheological Characterisation Of Thermogelling Chitosan/glycerol-phosphate Solutions. Carbohydrate Polymers, 2001;46: 39-47.
Berrada M, et al. Sustained release of poorly, water-soluble drugs from BST-Gel™. 6th U.S. - Japan Symposium on Drug Delivery Systems. Hawaii, December 2001. (362 KB)
Ruel-Gariepy E, et al. Thermosensitive chitosan based hydrogels for the delivery of macromolecules and hydrophilic drugs. 6th U.S. - Japan Symposium on Drug Delivery Systems. Hawaii, December 2001. (356 KB)
Jarry C, Chaput C, Chenite A, Renaud MA, Buschmann MD, Leroux JC. Effects of Steam Sterilization on New Thermogelling Chitosan-based Gels. Journal of Biomedical Materials Research, 2001;58 (1):127-135.
Jarry C et al. Effects of Polyol Additives on Autoclaved Chitosan Solutions. The 3rd Int. Symposium on Chitin Enzymology and the 4th Conference of the European Chitin Society, Senigallia, Italy, May 2001.
Jarry C et al. The Effects of Polyol Additives and Autoclaving on Thermogelling Chitosan-GP Systems. Annual meeting of the Society for Biomaterials, Minneapolis, USA, May 2001
Chenite A, Chaput C, Wang D, Combes C, Buschmann MD, Hoemann CD, Leroux JC, Binette F, Selmani A. Novel injectable neutral solutions of chitosan form biodegradeable gels in-situ. Biomaterials, 2000;21 (21): 2155-2161 .
Ruel-Gariepy E, Chenite A, Chaput C, Guirguis S, Leroux JC. Characterization of thermosensitive chitosan gels for the sustained delivery of drugs. Int. J. Pharm., 2000;203, 89-98.
Jarry C et al. Steam sterilization of a novel temperature-sensitive chitosan-based hydrogel. 2ième Symposium International sur les Biomatériaux Avancés, Montréal, Québec, Canada, June-July 2000.
Chaput C et al. Injectable Bone Grafting Materials based on Calcium-Phosphate/Chitosan-GP Formulations. ”, Trans Sixth World Biomaterials Congress, Kamuela HI, 2000;May15-20, 373.
Jarry C et al. Steam Sterilization or ý-Irradiation of Chitosan Materials: Effects on Performances of Thermogelling Chitosan-ß-Glycerophosphate Systems. Trans Sixth World Biomaterials Congress, Kamuela HI, 2000;May15-20, 373.
Jarry C et al. Steam sterilization of a novel temperature-sensitive chitosan based hydrogel. AAPS Pharm.Sci. 1999; 1:S-481. AAPS Annual Meeting and Exposition, New Orleans, USA.

BST-CarGel®

Hoemann C. et al. Chitosan-glycerol phosphate/blood implants elicit hyaline cartilage repair integrated with porous subchondral bone in microdrilled rabbit defects. OsteoArthritis and Cartilage (2007) 15, 78-89
Chevrier A et al. Chitosan-Glycerol Phosphate/Blood Implants Increase Cell Recruitment, Transient Vascularization and Subchondral Bone Remodeling in Drilled Cartilage Defects. OsteoArthritis and Cartilage (2007) 15, 316-327

More references for BST-CarGel®

Other references for BST-CarGel®

Hoemann CD, Hurtig M, Rossomacha E, Sun J, Chevrier AC, Shive MS, Buschmann MD. Chitosan/Glycerol Phosphate/Blood Implants Improve Cartilage Repaire in Ovine Microfracture Defects 2005 Journal of Bone and Joint Surg, AM 2005;87(12):2671-86
Chevrier A, Rossomacha E, Buschmann MD, and Hoemann CD. Optimization of Histoprocessing Methods to Detect Glycosaminoglycan, Collagen type I and Collagen type II in Decalcified Rabbit Osteochondral Sections 2005 J. Histotechnology, 28(3): 165-175
Rossomacha, E, Hoemann CD, Chevrier A, and Shive MS. 2005 Microwave histoprocessing: one-step dehydration and clearing of articular cartilage and synovial tissue. HistoLogic, 2005;38(2):25
Hoemann CD, Hurtig M, Sun J, McWade D, Rossomacha E, Shive MS, McKee MD, Buschmann MD. Full-thickness Cartilage Repair Using an Injectable Chitosan Scaffold, IXth Canadian Connective Tissue Conference, Montreal, QC July 4-6, 2003.
Hoemann CD, Hurtig M, Sun J, McWade D, Rossomacha E, Shive MS, McKee MD, Buschmann MD, Full-Thickness Cartilage Repair Using an Injectable Chitosan Scaffold, BST-CarGel, 3rd Annual Engineering Tissue Growth, Pittsburgh, PA, March 17-20, 2003.
Shive M, Hoemann C, Hurtig M, Ranger P, Sun J, McWade D, Rossomacha E, McKee M, Buschmann MD, “Full-Thickness Cartilage Repair Using an Injectable Chitosan Scaffold, BST-CarGel”, 7th International Conference of Orthopaedics, Biomechanics, Sports Rehabilitation, Assisi, Italy Nov 21-23, 2003.
Hoemann CD, Sun J, Chrzanowski V, Buschmann MD. A Multivalent Assay to Detect Glycosaminoglycan, protein, Collagen, RNA, and DNA content in milligram samples of cartilage or hydrogel-based repair cartilage. Anal Biochem, 2002;300(1):1-10.
Hoemann CD, Sun J, Légaré A, McKee MD, Gupta A, Buschmann MD. A novel chitosan based injectable cell delivery vehicle (678 KB). 6th U.S. - Japan Symposium on Drug Delivery Systems. Hawaii, December 2001.
Hoemann CD, Sun J, Légaré A, McKee MD, Ranger P, Buschmann MD. A Thermosensitive Polysaccharide Gel for Cell Delivery in Cartilage Repair. Transactions Orthopaedic Research Society. 26: 626. San Francisco. February 2001.
Hoemann CD, Sun J, Légaré A, McKee MD, Buschmann MD. Tissue Engineering of Cartilage using an Injectable Chitosan-Based Cell-Delivery Vehicle. Canadian Chemical Engineering Conference. Montreal, October 2000.
Hoemann CD, Sun J, Binette F, Buschmann MD. A Multivalent Assay to Quantitate Glycosaminoglycan, DNA, RNA, Protein, and Collagen in Milligram Samples of Cartilage or Tissue Engineered Cartilage Constructs. Trans Federation Eurpoean Connective Tissue Societies. Patras, Greece, July 2000.
Hoemann CD, Sun J, Binette F, Légaré A, McKee MD, Buschmann MD. Neocartilage Formation in vitro and in vivo Using an Injectable Chitosan-Based Cell-Delivery Vehicle That Gels and Adheres In-Situ. Trans Federation European Connective Tissue Societies. Patras, Greece, July 2000.